Apo E Gene Testing and You
By Pamela McDonald
A large percentage of heart disease is known to be genetic. So,
as experience with patients has also shown me, even more
important than looking beyond total cholesterol levels is
testing for the number one gene that affects cholesterol and
heart disease — Apo E.
Most people are still not sure how they feel about genetic
testing or what to do with genetic testing results if they have
been tested. Because it is such a new technology, most people
have never discussed a genetic test with a medical provider, let
alone had one performed. Yet if you have had a baby born into
your family in the past few years, chances are the baby has had
a genetic test for phenylketonuria (PKU). The routine genetic
testing of newborns can identify genetic disorders that must be
treated early in life and is the most widespread use of genetic
testing. All 50 states have passed laws requiring that newborns
be tested for PKU because if it is not identified and treated
very early with dietary restrictions, it causes mental
retardation.
While the medical industry is in its infancy with respect to
genetic testing and handling the results of that testing, we
know enough to say that proper genetic testing can provide you
with some important information that can help you determine how
to best protect or improve your health. This does not mean that
everyone should be gene tested. Gene testing has some involved,
complicated medical and ethical issues associated with it. I
won't get into the debate about genetic testing from a
philosophical standpoint, but rather, share with you certain
conditions under which you may — or may not — want to consider
genetic testing. Your decision about whether or not to take the
Apo E genotype test should be made with the help of a
practitioner, ideally the one who will then order the test for
you if you decide in favor. I will offer guidelines below to
help you and your practitioner in making the right decision for
you.
Drawbacks of Testing
The decision to get tested for the Apo E gene is not easy, and
one of the main reasons is because your health insurance company
and your employer could find out that you have an above average
risk of developing Alzheimer disease or cardiovascular disease.
Besides their knowing, you might rather not know that unless you
make major changes to how you live your life, you have a 90
percent chance of developing Alzheimer disease. If you are
considering the test because your family has a history of
Alzheimer disease, or you have very high cholesterol, you should
talk with a medical provider who has experience performing these
tests and can help keep your test results confidential.
The Apo E test, along with an advanced cholesterol test, can
give you clear nutritional direction and guidance. The question
then becomes whether you need an Apo E test, or just advanced
cholesterol testing. Personally, I think it depends on what you
want, need, and are willing to do. I do not recommend that
testing be done just to find your risk of contracting Alzheimer
disease. Rather, the decision to be tested should be based on
your desire to obtain the information necessary for proper
nutritional guidance and assistance in preventing chronic
illness.
Reasons for Doing Genetic Testing
Indications and warning signs that may be a reason for genetic
testing are a personal history of:
• severe cardiovascular disease
• Alzheimer disease
• Parkinson disease
• severe neurological disease
• gout
• alcoholism
• high triglycerides and/or LDL
• insulin resistance or diabetes
• substance abuse
• morbid obesity
• depression/anxiety disorder or other mood disorders
• confirmation of a high cholesterol disorder potentially being
affected by the Apo E gene
• confirmation of a diagnosis of late onset Alzheimer disease
in a symptomatic adult or to reduce risk with dietary
prescription
• assistance with treatment of multiple sclerosis by dietary
prescription
• assistance with treatment of Parkinson disease by dietary
prescription
At the same time, if you have one of the following chronic
illnesses or conditions and you are not getting better with your
current care plan, you may want to consider getting an Apo E
test to help improve your dietary patterns. Here are just a few
conditions that I have seen find exceptional success with
dietary change related to an Apo E genotype:
• acne
• arthritis
• gout
• diabetes
• depression
• alcoholism
• chronic pain
• ADD and ADHD
• high cholesterol
• cardiovascular disease
• hypertension
• Parkinson disease
• multiple sclerosis
• severe peri-menopausal symptoms
• anxiety
• chronic obesity
• fibromyalgia
• insulin resistance
• insomnia
• menopausal symptoms
• glucose intolerance
I strongly recommend that you find a medical provider who has
been trained in the advancing field of genetic heart disease and
in integrative nutritional medicine to support you.
About the Author: Pamela McDonald is a leading Integrative
Medicine Nurse Practitioner, who specializes in the prevention
of heart and Alzheimer's disease, and chronic illness. To learn
more about her groundbreaking book, and program - visit
http://www.apoegenediet.com. To subscribe to her free APO E Gene
Diet Health Notes - send a blank email to Info@ApoeGenediet.com.
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