Exciting Anti-Aging Research: Bergamot Stimulated AMPK Release May Keep Your Body Healthy ADVERTISEMENT
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Declining health and increased vulnerability to disease are characteristics of aging. In many ways this seems almost paradoxical - with advances in medical science comes the promise of longevity and indeed people are enjoying longer lives, but over time the body gradually loses vigor. It's not uncommon for elderly people to be afflicted with at least of one the following ailments:
- cardiovascular disease
Although medical science has yet to understand precisely how the human body enters a state of physical decline, we do know that part of the reason is a gradual loss of cellular energy and with it, increased susceptibility to internal and external stressors.
In this article, I'm going to talk about some of the stressors and how supplementing your diet with bergamot may help your body to remain healthy for a longer period of time.
Aging and Metabolism
God has given us a set amount of time to live; at present He does not want these bodies to continue indefinitely. Therefore He incorporated an almost incalculable number of mechanisms into the functioning of the human body, their interaction can keep the internal machinery running smoothly i.e. prolonged health or fall into a state of illness and eventual death.
To get a better appreciation of this, I'm going to tell you some interesting facts about the physiology and biochemistry that we rely on every second of our lives.
The human body is amazingly designed, it's composed of trillions of living cells and each of them is equipped with internal machinery and the ability to regulate itself and to regulate and be regulated by other cells.
We should think of cells as living machines and as with any machine, they require a battery, a steady supply of fuel and a means to remove excess waste.
Food is the fuel of the body; in the stomach and small intestine, food is digested i.e. broken into chemicals which are eventually transported to each cell. From there the fuel is used by the cells for energy.
Mitochondia are the cellular batteries that I mentioned above. You maybe surprised to know that our cells "breathe". Mitochondria use oxygen from cellular respiration to produce adenosine triphosphate (ATP). ATP is a high energy molecule; when it is used up, ATP is broken down to adenosine diphosphate (ADP) and eventually adenosine monophosphate (AMP). AMP is the "end of the line" so to speak, the cell would be out of energy if it were left with only AMP.
Fortunately, the body produces 5'adenosine monophosphate-activated protein kinase (AMPK) which is a special chemical that makes good use of AMP.
One of the functions of AMPK is to recognize when cells are running low on ATP.
When ATP is low, AMPK helps stimulate production of more ATP through a variety of mechanisms including:
- fatty acid oxidation - breaking down fat for energy
- glycolysis - converting stored glucose for energy
- increased synthesis of a protein that transports glucose across cell membranes
- increased production of mitochondrial enzymes involved in the production of oxygen carrier molecule
Unfortunately, we gradually lose energy as we age. Although aging is a natural part of living, some of its consequences can be very problematic, because they can lead to metabolic syndrome and with it a host of potentially deadly illnesses.
Metabolic Syndrome - the Killer Within
Metabolic syndrome is a name given to a condition that encompasses a variety of inter-related illnesses. I've written several articles discussing its potential danger to the human body. In short, people diagnosed with metabolic syndrome often have the following ailments:
- type 2 diabetes
- high cholesterol
- high blood pressure
Each of the above illnesses are serious in and of themselves, but imagine how much more deadly they are when a person is afflicted with all of them. Even worse, fatty liver disease - a condition wherein the liver accumulates excess fat - often accompanies metabolic syndrome.
Does this mean that we are destined to be destroyed by this affliction? Not necessarily.
AMPK and Bergamot May Hinder Metabolic Syndrome
Medical scientists have been devoting a great deal of study to finding ways to combat age-related illnesses. Recently research teams have discovered that bergomot polypehlic fraction (BPF) can work with AMPK to combat the effects of metabolic syndrome.
Aging populations are susceptible to metabolic syndrome which can have a detrimental effect on quality and quantity of life. Fortunately, God has created the human body to be able to make use of food for fuel and provided numerous mechanisms to help the body function efficiently.
AMPK is an enzyme that is manufactured by every cell of the body and is involved in energy production for cellular metabolism. Therefore, AMPK is a chemical that can have a positive effect on metabolic syndrome because it is necessary for health and longevity i.e. it slows down the aging process.
Bergamot polyphenolic fraction are chemicals that come directly from bergamot citrus fruit. Bergamot polyphenolic fraction is a natural activator of AMPK, thus bergamot polyphenolic fraction may also help slow down the effects of aging.
Health supplements should not be mistaken for medicinal drugs that would be prescribed by physicians for treatment of any given disease.
***Disclaimer: This article is not endorsed by the US Food and Drug Administration (FDA). People should consult their physician before making changes to their diet. The content in this sponsored article and elsewhere on Living Fit, Healthy and Happy(SM) is for informational purposes only, and is not intended to substitute for medical advice, treatment or diagnosis. People should consult their physician before making changes to their diet.
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